Studies

Scientific TPS investigations at the Medical University of Vienna (Prof. Beisteiner) and international cooperation partners:

Transcranial Pulse Stimulation with Ultrasound in Alzheimer's Disease-A New Navigated Focal Brain Therapy.

Beisteiner R, Matt E, Fan C, Baldysiak H, Schönfeld M, Philippi Novak T, Amini A, Aslan T, Reinecke R, Lehrner J, Weber A, Reime U, Goldenstedt C, Marlinghaus E, Hallett M, Lohse-Busch H.
Adv Sci (Weinh). 2019 Dec 23;7(3):1902583.
DOI: 10.1002/advs.201902583

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Transcranial ultrasound pulse stimulation reduces cortical atrophy in Alzheimer's patients: A follow-up study

Popescu T, Pernet C, Beisteiner R.
Alzheimers Dement (N Y). 2021 Feb 25;7(1):e12121.
DOI: 10.1002/trc2.12121

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Transcranial pulse stimulation (TPS) improves depression in AD patients on state-of-the-art treatment.

Matt E, Dörl G, Beisteiner R. 
Alzheimers Dement (N Y). 2022 Feb 10;8(1):e12245.
DOI: 10.1002/trc2.12245

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Transcranial Pulse Stimulation (TPS) - A highly focused brain stimulation therapy with 3D navigation.

Beisteiner R, Hallett M.
Clin Neurophysiol. 2022 Jan 31:S1388-2457(22)00145-6.
DOI: 10.1016/j.clinph.2022.01.127

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Reply to "Transcranial Pulse Stimulation (TPS) - A highly focused brain stimulation therapy with 3D navigation"

Darmani G, Chen R.
Clin Neurophysiol. 2022 Apr;136:249.
DOI: 10.1016/j.clinph.2022.01.129. Epub 2022 Feb 1. PMID: 35168853.

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First evidence of long-term effects of transcranial pulse stimulation (TPS) on the human brain

Matt E, Kaindl L, Tenk S, Egger A, Kolarova T, Karahasanović N, Amini A, Arslan A, Sariçiçek K, Weber A, Beisteiner R.
J Transl Med. 2022 Jan 15;20(1):26.
DOI: 10.1186/s12967-021-03222-5

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Effects of Transcranial Pulse Stimulation on Young Adults With Symptoms of Depression: A Pilot Randomised Controlled Trial Protocol.

Cheung T, Ho J, Yeung J, Fong LS, Fong K, Fong T, Kranz G, Beisteiner R, Cheng C.
Frontiers Neurol, 2022
DOI:10.3389/fneur.2022.861214

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Evaluating the Safety and Efficacy of Transcranial Pulse Stimulation on Autism Spectrum Disorder: A Double-Blinded, Randomized, Sham-Controlled Trial Protocol

Cheung T, Ho YS, Fong KH, Lam YTJ, Li MH, Tse AC, Li CT, Cheng CP, Beisteiner.
Int J Environ Res Public Health. 2022 Nov 24;19(23):15614.
DOI: 10.3390/ijerph192315614. PMID: 36497688; PMCID: PMC9737330.

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Safety of Clinical Ultrasound Neuromodulation

Radjenovic S, Dörl G, Gaal M, Beisteiner R.
Brain Sci. 2022, 12, 1277.
DOI: 10.3390/brainsci12101277

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Functional Specificity of TPS Brain Stimulation Effects in Patients with Alzheimer’s Disease: A Follow-up fMRI Analysis

Dörl G, Matt E, Beisteiner R.
Neurol Ther, 2022 Sep;11(3):1391-1398
DOI: 10.1007/s40120-022-00362-8. Epub 2022 May 28. PMID: 35633496; PMCID: PMC9338196.

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Other scientific TPS investigations:

Comparison of Transcranial Focused Ultrasound and Transcranial Pulse Stimulation for Neuromodulation: A Computational Study

Truong DQ, Thomas C, Hampstead BM, Datta A.
Neuromodulation. 2022 Jun;25(4):606-613.
DOI:10.1016/j.neurom.2021.12.012. Epub 2022 Feb 4. PMID: 35125300.

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Retrospective real-world pilot data on transcranial pulse stimulation in mild to severe Alzheimer's patients

Cont C, Stute N, Galli A, Schulte C, Logmin K, Trenado C, Wojtecki L.
Front Neurol. 2022 Sep 14;13:948204.
DOI: 10.3389/fneur.2022.948204. PMID: 36188380; PMCID: PMC9515314.

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