Studies
Scientific TPS investigations at the Medical University of Vienna (Prof. Beisteiner) and international cooperation partners:
Transcranial Pulse Stimulation with Ultrasound in Alzheimer's Disease-A New Navigated Focal Brain Therapy.
Beisteiner R, Matt E, Fan C, Baldysiak H, Schönfeld M, Philippi Novak T, Amini A, Aslan T, Reinecke R, Lehrner J, Weber A, Reime U, Goldenstedt C, Marlinghaus E, Hallett M, Lohse-Busch H.
Adv Sci (Weinh). 2019 Dec 23;7(3):1902583.
DOI: 10.1002/advs.201902583
Treating the brain at the speed of sound
Beisteiner R, Lozano A
Brain Stimul. 2020 Jul-Aug;13(4):1087-1088.
doi: 10.1016/j.brs.2020.04.020. Epub 2020 May 6. PMID: 32387244
Transcranial Ultrasound Innovations Ready for Broad Clinical Application
Beisteiner R, Lozano AM
Adv Sci (Weinh). 2020 Oct 27;7(23):2002026.
doi: 10.1002/advs.202002026. PMID: 33304757; PMCID: PMC7709976
Transcranial ultrasound pulse stimulation reduces cortical atrophy in Alzheimer's patients: A follow-up study
Popescu T, Pernet C, Beisteiner R.
Alzheimers Dement (N Y). 2021 Feb 25;7(1):e12121.
DOI: 10.1002/trc2.12121
First evidence of long-term effects of transcranial pulse stimulation (TPS) on the human brain
Matt E, Kaindl L, Tenk S, Egger A, Kolarova T, Karahasanović N, Amini A, Arslan A, Sariçiçek K, Weber A, Beisteiner R.
J Transl Med. 2022 Jan 15;20(1):26.
DOI: 10.1186/s12967-021-03222-5
Transcranial Pulse Stimulation (TPS) - A highly focused brain stimulation therapy with 3D navigation.
Beisteiner R, Hallett M.
Clin Neurophysiol. 2022 Jan 31:S1388-2457(22)00145-6.
DOI: 10.1016/j.clinph.2022.01.127
Human Ultrasound Neuromodulation: State of the Art
Beisteiner R.
Brain Sci. 2022 Feb 1;12(2):208.
doi: 10.3390/brainsci12020208. PMID: 35203971; PMCID: PMC8870582
Transcranial pulse stimulation (TPS) improves depression in AD patients on state-of-the-art treatment.
Matt E, Dörl G, Beisteiner R.
Alzheimers Dement (N Y). 2022 Feb 10;8(1):e12245.
DOI: 10.1002/trc2.12245
Effects of Transcranial Pulse Stimulation on Young Adults With Symptoms of Depression: A Pilot Randomised Controlled Trial Protocol.
Cheung T, Ho J, Yeung J, Fong LS, Fong K, Fong T, Kranz G, Beisteiner R, Cheng C.
Frontiers Neurol, 2022
DOI:10.3389/fneur.2022.861214
Functional Specificity of TPS Brain Stimulation Effects in Patients with Alzheimer’s Disease: A Follow-up fMRI Analysis
Dörl G, Matt E, Beisteiner R.
Neurol Ther, 2022 Sep;11(3):1391-1398
DOI: 10.1007/s40120-022-00362-8. Epub 2022 May 28. PMID: 35633496; PMCID: PMC9338196.
Evaluating the Safety and Efficacy of Transcranial Pulse Stimulation on Autism Spectrum Disorder: A Double-Blinded, Randomized, Sham-Controlled Trial Protocol
Cheung T, Ho YS, Fong KH, Lam YTJ, Li MH, Tse AC, Li CT, Cheng CP, Beisteiner.
Int J Environ Res Public Health. 2022 Nov 24;19(23):15614.
DOI: 10.3390/ijerph192315614. PMID: 36497688; PMCID: PMC9737330.
Safety of Clinical Ultrasound Neuromodulation
Radjenovic S, Dörl G, Gaal M, Beisteiner R.
Brain Sci. 2022, 12, 1277.
DOI: 10.3390/brainsci12101277
Effects of Transcranial Pulse Stimulation (TPS) on Adults with Symptoms of Depression-A Pilot Randomized Controlled Trial
Cheung T, Li TMH, Ho YS, Kranz G, Fong KNK, Leung SF, Lam SC, Yeung WF, Lam JYT, Fong KH, Beisteiner R, Xiang YT, Cheng CPW
Int J Environ Res Public Health. 2023 Jan 28;20(3):2333.
doi: 10.3390/ijerph20032333. PMID: 36767702; PMCID: PMC9915638
Ultrasound Neuromodulation as a New Brain Therapy
Beisteiner R, Hallett M, Lozano AM
Adv Sci (Weinh). 2023 Mar 24:e2205634.
doi: 10.1002/advs.202205634. Epub ahead of print. PMID: 36961104
Evaluating the efficacy and safety of transcranial pulse stimulation on adolescents with attention deficit hyperactivity disorder: Study protocol of a pilot randomized, double-blind, sham-controlled trial
Cheung T, Chau B, Fong KH, Lam JYT, Lo H, Li MH, Li AMMC, Beisteiner R, Lei S, Yee BK, Cheng CPW
Front Neurol. 2023 Mar 28;14:1076086.
doi: 10.3389/fneur.2023.1076086. PMID: 37056363; PMCID: PMC10086174
Other scientific TPS investigations:
Comparison of Transcranial Focused Ultrasound and Transcranial Pulse Stimulation for Neuromodulation: A Computational Study
Truong DQ, Thomas C, Hampstead BM, Datta A.
Neuromodulation. 2022 Jun;25(4):606-613.
DOI:10.1016/j.neurom.2021.12.012. Epub 2022 Feb 4. PMID: 35125300.
Retrospective real-world pilot data on transcranial pulse stimulation in mild to severe Alzheimer's patients
Cont C, Stute N, Galli A, Schulte C, Logmin K, Trenado C, Wojtecki L.
Front Neurol. 2022 Sep 14;13:948204.
DOI: 10.3389/fneur.2022.948204. PMID: 36188380; PMCID: PMC9515314.
Transcranial pulse stimulation in Alzheimer's disease
Chen X, You J, Ma H, Zhou M, Huang C.
CNS Neurosci Ther. 2023 Jul 20.
doi: 10.1111/cns.14372. Epub ahead of print. PMID: 37469252.
Transcranial pulse stimulation in the treatment of mild neurocognitive disorders
Fong TKH, Cheung T, Ngan STJ, Tong K, Lui WYV, Chan WC, Wong CSM, Cheng CPW.
Ann Clin Transl Neurol. 2023 Aug 21.
doi: 10.1002/acn3.51882. Epub ahead of print. PMID: 37607114.
The Emergence of Functional Ultrasound for Noninvasive Brain-Computer Interface
Zheng H, Niu L, Qiu W, Liang D, Long X, Li G, Liu Z, Meng L.
Research (Wash D C). 2023 Aug 15;6:0200.
doi: 10.34133/research.0200. PMID: 37588619; PMCID: PMC10427153.